Histological modification in TRAM flap in rats treated with pentoxifylline

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Histological modification in TRAM flap in rats treated with pentoxifylline.

PURPOSE To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pentoxifylline. METHODS 32 male, Wistar-EPM rats were divided into two groups. Control group (C): 0.5 ml of saline, intraperitoneally, once a day, for seven days before flap elevation; PTX group (P): pentoxifylline (20mg/kg/day), intraperitoneally, for seven days before flap elevation. After t...

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Background and Aim: Despite the advances in maxillofacial surgery, impaired bone healing remains a concern for surgical teams. Effects of sildenafil and pentoxifylline on healing of bone fractures have not been well investigated. This study aimed to assess the effects of sildenafil and pentoxifylline phosphodiesterase inhibitors on healing of mandibular fractures in rats. Materials and Methods...

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ژورنال

عنوان ژورنال: Acta Cirurgica Brasileira

سال: 2014

ISSN: 0102-8650

DOI: 10.1590/s0102-86502014001400007